# Treatment Resistance

This section gathers treatment-resistance topics that cut across cancer types, regimens, and biomarkers.

Use it when the question is about **why treatment may stop working**, not just what symptom it causes.

### Start here

* [Overview](/myhealingcommunity-docs/treatment-resistance/treatment-resistance/treatment-resistance-overview.md)
* [Dormant Cancer Cells](/myhealingcommunity-docs/treatment-resistance/treatment-resistance/dormant-cancer-cells-2.md)
* [Senescence — The Second Escape Route](/myhealingcommunity-docs/treatment-resistance/treatment-resistance/senescence-the-second-escape-route.md)
* [Drug Metabolism & Supplement Interactions](/myhealingcommunity-docs/treatment-resistance/treatment-resistance/drug-metabolism-and-supplement-interactions.md)
* [TP53 in Cancer](/myhealingcommunity-docs/testing-monitoring-and-biomarkers/tp53-in-cancer.md)

### Use this section for

* resistance mechanisms
* progression patterns
* pharmacokinetic and drug-exposure questions
* biomarker-driven treatment-escape logic
* dormancy, residual disease, and reactivation-risk questions
* therapy-induced senescence, SASP biology, and senolytic follow-up questions
* cross-cancer resistance pages that do not fit one disease hub

### Related hubs elsewhere

* [TP53 in Cancer](/myhealingcommunity-docs/testing-monitoring-and-biomarkers/tp53-in-cancer.md) in [Testing, Monitoring & Biomarkers](/myhealingcommunity-docs/testing-monitoring-and-biomarkers/testing-monitoring-and-biomarkers-overview.md)
* [HER2CLIMB Resistance Mechanisms](/myhealingcommunity-docs/breast-cancer/her2-positive/her2climb/her2climb-resistance-mechanisms.md) in [Breast Cancer](/myhealingcommunity-docs/breast-cancer/breast-cancers-overview.md)

### Current status

This hub is still early.

It now has its own home anchor and overview so resistance topics can grow without being mixed into side-effect navigation.

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This information is for education only. It is not medical advice, diagnosis, or treatment. Please speak with a qualified clinician before making changes to care, medication, or supplement use.
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© 2026 Abbey Mitchell. All rights reserved. Please share by URL rather than copying page text.
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```
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```

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Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.