# Immune Effects

Mebendazole's immune relevance is especially interesting because of its **ERK / MAPK duality**.

### Immune overview

In tumour cells, mebendazole appears to suppress ERK-related survival signalling. In immune cells, it may activate ERK-linked pathways in ways that support anti-tumour immune responses.

### Why this matters

That means mebendazole may do two things at once:

* weaken ERK-driven tumour survival
* strengthen parts of the immune response against the tumour

This is one of the reasons it stands out among repurposed and integrative oncology candidates.

### Practical interpretation

The immune discussion remains emerging, but it strengthens the case for mebendazole as a multi-pronged adjunct rather than a simple anti-mitotic drug.

### Key References

Mebendazole as a Candidate for Drug Repurposing in Oncology\
<https://pmc.ncbi.nlm.nih.gov/articles/PMC6769799/>

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