# Prostate Cancer

Itraconazole has one of its clearest early clinical signals in **metastatic castration-resistant prostate cancer**.

### Overview

This is one of the most important clinical pages in the itraconazole topic because it includes prospective phase II data rather than preclinical logic alone.

### Key human data

* A phase II study using **600 mg daily** reported a PSA progression-free survival rate of 48% at 24 weeks in men with metastatic castration-resistant prostate cancer
* This is one of the stronger early clinical indications that itraconazole may have real biological activity in an oncology setting

### Practical interpretation

The prostate cancer page is central to the itraconazole repurposing story because it moves beyond theory and into measurable human clinical signal.

### References

Repurposing itraconazole as an anticancer agent\
<https://pmc.ncbi.nlm.nih.gov/articles/PMC5536437/>

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